Andrew G. Chapple PhD

Andrew G. Chapple PhD

Assistant Professor

Dr. Chapple is an expert in adaptive clinical trial designs, particularly Bayesian methods. His 2019 paper “A hybrid Phase I-II/III clinical trial design allowing for dose re-optimization in Phase III” proposed a new framework for seamless drug development through the three stages of clinical trial design. This paper was recognized globally by the statistical community when it received the award for “Best Paper” from Biometrics, a top tier statistical journal.Dr. Chapple has produced many new trial designs and methods, which are accompanied with user-friendly R packages. Dr. Chapple trained under Dr. Peter Thall at MD Anderson, who is a pioneer in Bayesian adaptive trials. He later refined these skills working with cancer researchers from other institutions. Dr. Chapple’s adaptive trial designs were used to dose-find in pediatric brain tumors in a trial conducted at Harvard and the Dana Farber Cancer Center.Dr. Chapple has designed hundreds of studies and has supported many research departments at LSUHSC including: Orthopedics, OBGYN, Hematology Oncology, Dermatology, Oral Surgery, Endodontics, Cancer, Virology, Cellular Biology, Inflammation, and treatment disparities research. As a joint professor in Orthopedics, Dr. Chapple works on large scale electronic records databases which requires processing longitudinal information from patients on hospital encounters, diagnoses, procedures, prescriptions, and lab values.

LCRC Faculty

Asim Abdel-Mageed DVM PhD
Therapeutics & Diagnostics
Tulane University School of Medicine
Suresh K. Alahari PhD
Therapeutics & Diagnostics
LSU Health - New Orleans
Wayne L. Backes PhD
Tumor Biology
LSU Health - New Orleans
Victoria P. Belancio PhD
Genes & Environment
Tulane University School of Medicine
Earl "Nupsius" Benjamin-Robinson DrHSc CPH
Population Sciences
Louisiana Cancer Research Center
Tom Bishop PhD
Genes & Environment
Louisiana Tech University
David Blask MD PhD
Tumor Biology
Tulane University School of Medicine
Levon Bostanian PhD
Therapeutics & Diagnostics
Xavier University
J. Quincy Brown PhD
Therapeutics & Diagnostics
Tulane University School of Medicine