Over the past decade research has provided a tremendous understanding of the molecular events leading to cancer. These molecular changes represent the ideal targets for development of new diagnostic and therapeutic strategies. Most of the molecular changes that cause cancer can be found in a broad range of different tumor sites and therefore research in these areas cannot be well categorized by individual tumor site. Our goal is facilitate research and clinical studies that take advantage of these new advances. Our approach includes laboratory, clinical and population sciences research. Our research themes are built around the needs of the medically underserved in Louisiana, as well as the strengths of our Consortium institutions and our investigators.