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06/12/2019

LCRC’s Biospecimen Core Lab’s Role in Cancer Research

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5/20/2019

LCRC’s Annual Retreat, 2019
Almost 200 researchers gathered at Xavier University in May for the annual Louisiana Cancer Research Center’s scientific retreat. The daylong, off-site gathering has proven to be an effective way to promote additional collaborations among the organization. LCRC member researchers from LSU, Tulane, Xavier and Ochsner presented dozens of posters of their research, from cancer genetics, immunology, molecular signaling, population sciences and clinical and translational research.

Zhe Wang, Phd lectured on “Sulfatase activity measurement in human body fluids for point-of-care cancer diagnosis.”

Yaguang Xi, MD,PhD, spoke on “Sulindac and triple negative breast cancer,” Louis Spencer Krane, MD talked about “Advances in renal cell carcinoma” and LiLi, MD, PhD discussed “Targetable miRNAs in the colorectal cancer extracellular microenvironment.”

Xavier University Professor of Biochemistry and LCRC Associate Director Thomas Wiese told the group that fostering collaboration was “the whole idea” of these retreats. “We are all focused on our research throughout the year and there are a lot of collaborations between the LCRC.  As you go through the day and the poster sessions, please look for opportunities for more collaboration.” Wiese prompted fellow Xavier scientists by noting that he had specifically set aside some funding for LCRC- Xavier faculty to develop collaborations with LCRC faculty from other institutions.

“This is the thirteenth year we have held the LCRC Scientific Retreat and it is always well-attended,” said LCRC Chief Administrative Officer Sven Davisson.  “LCRC researchers are undertaking impactful cancer research and the opportunity to get them together in a single room, outside of the lab is always very productive.”

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5/9/2019
Every day, researchers are conducting cancer research in labs at the LCRC. Like Tiffany Kaul, pictured here, who is working with cancer cell lines as part of cancer genetics research.

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4/26/2019
La. Campaign for Tobacco-Free Living’s Response to HB 38
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4/24/2019
Precision Medicine: Tailoring Treatment to the Individual 

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4/24/2019
THE POWER OF PARTNERING: LOUISIANA CANCER RESEARCH CENTER
 HIGHLIGHTS STRIDES IN FEDERAL FUNDING AND CANCER-FIGHTING COLLABORATIONS

March 26, 2019, New Orleans, LA – As partner members of The Louisiana Cancer Research Center (LCRC), the state’s esteemed research institutions made important inroads in cancer research, prevention and diagnosis in 2018. The LCRC facilitates and supports the cancer-related research of members LSU Health New Orleans, Tulane University School of Medicine, Xavier University of Louisiana, Ochsner Health System and the LCRC’s smoking cessation program, The Louisiana Campaign for Tobacco-Free Living (TFL).

“Working together, LCRC members are generating the cross-institutional critical mass that is needed to qualify for some of the very large cancer research programs and the complex grants that require multiple investigators,” said Augusto Ochoa, MD, Co-Director, LCRC, Director, Stanley S. Scott Cancer Center, LSU Health New Orleans.

“We are stronger researchers when we work together and the LCRC is making it easier to bridge the silos that understandably exist among academic research institutions are located close to one another,” said Prescott Deininger, PhD, Co-Director LCRC and Director, Tulane Cancer Center.

In its annual report released today, the LCRC highlighted its scientific achievements of 2018, particularly clinical trials driven by precision medicine, which involves tailoring cancer treatments to a patient’s unique genetic profile. Other achievements include:

  • LCRC partners were awarded $23.6 million in cancer-related grants from the National Institutes of Health (NIH) in 2018 for a total of $355.6 million since 2002. Current funding is six-times higher than pre-LCRC award levels.
  • Creation of a Gulf South Clinical Trials Network, supported by the NCI Community Oncology Research Program (NCORP). This is a collaboration between LSUHSC/Ochsner/Mary Bird Perkins and LSU Health – Shreveport. The network provides advanced cancer clinical trials at 42 treatment sites, in Shreveport, Monroe, Alexandria, Lake Charles, Baton Rouge, Covington, Houma, Metairie, New Orleans, Slidell, Hattiesburg and Gulfport.
  • LCRC researchers based at LSU Health New Orleans received the first NIH planning grant for Specialized Programs of Research Excellence (SPOREs), ever awarded in Louisiana.
  • An LCRC researcher based at Tulane University received a four-year NCI award to develop a tool that has the potential to reduce the recurrence of prostate cancer.
  • LCRC funds, with NIH grant funding, have enabled significant progress on
  • The development of breast cancer therapeutics by researchers at Xavier University.
  • Six additional Louisiana cities, including Baton Rouge, passed comprehensive indoor-smoke free policies, because of the efforts of LCRC smoking cessation program, TFL, and its statewide partners.

In 2018, LCRC member institutions enrolled 1,071 patients in clinical trials, published 343 articles in scientific journals, and hosted 47 scientific seminars. “This depth of scientific research and collaboration does not happen in a vacuum.  LCRC has provided critical core infrastructure, laboratory and meeting spaces that foster collaboration and innovation,” said Sven Davisson, LCRC Chief Administrative Officer.

In Louisiana, LCRC members account for more than 80% of federal cancer research funding. Every $1 in NIH funding generates more than double that in local economic growth for a total economic impact of $64 million in Louisiana last year.

The LCRC also released its Strategic Framework document outlining the center’s plan for attaining designation as a National Cancer Institute Cancer Center, considered a pathway to even more increases in federal research awards. In an introductory letter, LCRC Board Chairs Dr. L. Lee Hamm, dean of Tulane University School of Medicine and Dr. Larry Hollier, chancellor of LSU Health New Orleans stated:   Through targeted faculty recruitment and strategic investments, our research programs are stronger than ever. National Cancer Institute funding has more than doubled. Our investigators have leveraged the collaborative infrastructure provided by the LCRC to successfully compete for major federal grants that would have otherwise been unlikely.

The LCRC recently began a search for a scientific director, a key component for NCI-Center designation. “Despite recent decreases in federal funding, the LCRC research grant totals have significantly exceeded pre-Katrina levels. We believe the strength of the LCRC collaboration will appeal to high-level candidates across the country,” Davisson said.

To read the LCRC Annual Report and Strategic Framework, click 2018 Annual Report and Strategic Framework, respectively.  http://www.louisianacancercenter.org/news/

For Quick Facts about the LCRC click here.

About the LCRC

Based in New Orleans, The Louisiana Cancer Research Center was created in 2002 by the Louisiana State Legislature. LCRC’s mission is to promote cancer education and to research the diagnosis, detection and treatment of cancer while pursuing a National Cancer Institute (NCI) designation. Website: louisianacancercenter.org; Facebook: @louisianacancercenter Twitter: @CancerLouisiana